Bioactivity | TASIN-1 hydrochloride is a selective inhibitor of truncated APC gene (adenomatous polyposis coli gene) and exerts cytotoxic effects through inhibition of cholesterol biosynthesis. TASIN-1 hydrochloride represents a potential strategy for prevention and intervention in CRC with mutant APC[1]. |
CAS | 1678515-13-3 |
Formula | C18H29ClN2O3S |
Molar Mass | 388.95 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhang L, et al. Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. Sci Transl Med. 2016 Oct 19;8(361):361ra140. |