| Bioactivity | Wnt/β-catenin agonist 3 hydrochloride is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 (compound 98) can be used for the research of osteoporosis[1]. |
| Invitro | Wnt/β-catenin agonist 3 盐酸盐 (compound 98; 24 h; HEK293 和 SW480 细胞) 在 120 μM 浓度下，显示出 54% 的细胞活性[1]。Wnt/β-catenin agonist 3 盐酸盐 (30 μM 和 60 μM; 24 h; HEK293 细胞) 是 β-Catenin 的激活剂，并沉积 β-Catenin[1]。Wnt/β-catenin agonist 3 盐酸盐 (11 μM; 4 d) 诱导 ST2 细胞系分化为成骨细胞和钙沉积[1]。 |
| Name | Wnt/β-catenin agonist 3 hydrochloride |
| Formula | C16H16Cl2N4O2 |
| Molar Mass | 367.23 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Cho JW, et al. Isoxazole derivatives and use thereof. WO2007078113A1. |
Wnt/β-catenin agonist 3 hydrochloride
CAS: F: C16H16Cl2N4O2 W: 367.23
Wnt/β-catenin agonist 3 hydrochloride is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 (compoun
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