Werner syndrome RecQ helicase-IN-2_product_DataBase

CAS: 2869954-51-6 F: C32H34F3N9O5 W: 681.66

Werner syndrome RecQ helicase-IN-2 (example 57) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and

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Bioactivity	Werner syndrome RecQ helicase-IN-2 (example 57) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research[1].
Invitro	Werner syndrome RecQ helicase-IN-2 (example 57)作用于 WRN ATPase 的IC50 值为100 nM，作用于 SW48和 DLD1 WRN-KO 细胞系的GI50 值分别是100 nM和大于10 μM[1]。
Name	Werner syndrome RecQ helicase-IN-2
CAS	2869954-51-6
Formula	C32H34F3N9O5
Molar Mass	681.66
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn). WO2022249060

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