Werner syndrome RecQ helicase-IN-1_product_DataBase

CAS: 2869954-34-5 F: C31H31ClF3N9O5 W: 702.08

Werner syndrome RecQ helicase-IN-1 (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and

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Bioactivity	Werner syndrome RecQ helicase-IN-1 (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research[1].
Invitro	Werner syndrome RecQ helicase-IN-1(example 42)作用于 WRN ATPase 的 IC50 值为100 nM，作用于 SW48 和 DLD1 WRN-KO 细胞系的 GI50 值分别是 50 nM和大于10 μM[1]。
Name	Werner syndrome RecQ helicase-IN-1
CAS	2869954-34-5
Formula	C31H31ClF3N9O5
Molar Mass	702.08
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn). WO2022249060

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