Bioactivity | WU-FA-01, a hydrogenated derivative of WU-FA-00, is an antibacterial agent that exhibits high levels of antibacterial activity against Gram-positive strains and also has some anti-inflammatory activity[1]. |
Invitro | WU-FA-01(0-25 µg/mL, 24 h) 对革兰氏阳性菌具有剂量依赖性的抑制剂作用,而对革兰氏阴性菌株没有抑制作用[1]。 |
In Vivo | WU-FA-01(2000-8000µg/mL) 对 TPA 诱导的小鼠耳模型水肿具有剂量依赖性的抑制作用,可以有效保护 TPA 诱导的皮肤炎症[1]。 Animal Model: |
Name | WU-FA-01 |
CAS | 882429-53-0 |
Formula | C34H52O9 |
Molar Mass | 604.77 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Pan-Pan Wu, et al. The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti-inflammatory agents. Infect Drug Resist. 2018 Oct 24;11:1945-1957. |