| Bioactivity | WDR5-MYC-IN-1 (compound 4o) is a potent WDR5-MYC interaction inhibitor with a Ki value of 1.0 µM. WDR5-MYC-IN-1 shows antiproliferative activity[1]. |
| Target | Ki: 1.0 µM (WDR5-MYC) |
| Invitro | WDR5-MYC-IN-1 (compound 4o) 显示出抗增殖活性，对 RAJI、RAMOS、SUDHL4、HL-60、H1299 细胞的 IC50 值分别为 1.52、1.51、2.20、5.32、7.40 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> WDR5-MYC-IN-1 相关抗体: Cell Proliferation Assay[1] Cell Line: |
| Formula | C12H10N4OS2 |
| Molar Mass | 290.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang H, et al. Identification of 5-Thiocyanatothiazol-2-amines Disrupting WDR5-MYC Protein-Protein Interactions. ACS Med Chem Lett. 2024 Jul 1;15(7):1143-1150. |