| Bioactivity | Estromustine (EoM) is the active metabolite of Estramustine phosphate (HY-13627A). Estromustine binds to mutant androgen receptor (m-AR) with EC50 of 2.6 μM in LNCaP, exhibits cytotoxicity in human prostate cells LNCaP with IC50 of 9.73 μM[1]. |
| CAS | 62899-40-5 |
| Formula | C23H29Cl2NO3 |
| Molar Mass | 438.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang LG, et al., Androgen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor. Biochem Pharmacol. 1998 May 1;55(9):1427-33. |
Estromustine
CAS: 62899-40-5 F: C23H29Cl2NO3 W: 438.39
Estromustine (EoM) is the active metabolite of Estramustine phosphate (HY-13627A). Estromustine binds to mutant androgen
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.