| Bioactivity | WD6305 is a potent METTL3-targeted PROTAC degrader. WD6305 selectively reduces the METTL3 and METTL14 complex. WD6305 inhibits m6A modification and the proliferation of AML cells and promotes apoptosis. WD6305 can be used for the research of leukemic[1]. |
| Name | WD6305 |
| Formula | C61H75F2N11O5S |
| Molar Mass | 1112.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Du W, et al. Discovery of a PROTAC degrader for METTL3-METTL14 complex. Cell Chem Biol. 2024 Jan 2:S2451-9456(23)00439-7. |