Bioactivity | W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth[1]. |
Name | W-13 hydrochloride |
CAS | 88519-57-7 |
Formula | C14H18Cl2N2O2S |
Molar Mass | 349.28 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tallant EA, et, al. Calmodulin antagonists elevate the levels of 32P-labeled polyphosphoinositides in human platelets. Biochem Biophys Res Commun. 1985 Aug 30;131(1):370-7. [2]. Strobl JS, et, al. Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. J Pharmacol Exp Ther. 1992 Oct;263(1):186-93. |