PeptideDB

Vimnerixin

CAS: 1418112-77-2 F: C19H25FN4O5S2 W: 472.55

Vimnerixin (AZD4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2). Vimnerixin h
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Bioactivity Vimnerixin (AZD4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2). Vimnerixin has the potential for the research of inflammatory disease[1].
Target CXCR2
In Vivo Assessment of Pharmacokinetics (PK) profile of Vimnerixin in rat and dog[1]. In Vivo PK
Name Vimnerixin
CAS 1418112-77-2
Formula C19H25FN4O5S2
Molar Mass 472.55
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Gardiner P, et al. Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs. Drug Metab Dispos. 2019;47(8):865-873.