| Bioactivity | VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.IC50 value:Target: Renin |
| Name | VTP-27999 Hydrochloride |
| CAS | 1264191-73-2 |
| Formula | C26H42Cl2N4O5 |
| Molar Mass | 561.54 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Lanqi Jia et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751 [2]. New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin. Hypertension. 2013 May;61(5):1075-1082. [3]. Ishchenko A, et al. Structure-based design technology contour and its application to the design of Renin inhibitors.J Chem Inf Model. 2012 Aug 27;52(8):2089-97. Epub 2012 Jul 25. |
VTP-27999 Hydrochloride
CAS: 1264191-73-2 F: C26H42Cl2N4O5 W: 561.54
VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.IC50 value:
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