| Bioactivity | Adrenalone hydrochloride is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone hydrochloride is an inhibitor of dopamine β oxidase. Adrenalone hydrochloride is chemically similar to known norepinephrine transporter (NET) ligands with an IC50 of 36.9 μM[1][2]. |
| Invitro | Adrenalone hydrochlorideis a topical nasal decongestant, hemostatic, and vasoconstrictor, is a keton form of the natural substrate epinephrine[1]. Adrenalone hydrochloride inhibits the activity of dopamine β-oxidase. Adrenalone inhibits substrate transport by NET[2]. |
| Name | Adrenalone hydrochloride |
| CAS | 62-13-5 |
| Formula | C9H12ClNO3 |
| Molar Mass | 217.65 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light, stored under nitrogen *该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
| Reference | [1]. M GOLDSTEIN,et al. Inhibition of dopamine beta oxidase by adrenalone. Nature.1961 Dec 16;192:1081. [2]. Avner Schlessinger, et al. Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15810-5. |
Adrenalone hydrochloride
CAS: 62-13-5 F: C9H12ClNO3 W: 217.65
Adrenalone hydrochloride is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone hydrochlo
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