| Bioactivity | VEGFR-IN-4 (Compound 6e) is an epidermal growth factor receptor (EGFR) inhibitor. VEGFR-IN-4 has potent antiproliferative activity with an IC50 value of 24.6nM against HCC827 cells[1]. |
| Name | VEGFR-IN-4 |
| CAS | 3000483-29-1 |
| Formula | C19H19ClN6O3S |
| Molar Mass | 446.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zuo Y, et al. Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation. Eur J Med Chem. 2023 Dec 29;265:116106. |
VEGFR-IN-4
CAS: 3000483-29-1 F: C19H19ClN6O3S W: 446.91
VEGFR-IN-4 (Compound 6e) is an epidermal growth factor receptor (EGFR) inhibitor. VEGFR-IN-4 has potent antiproliferativ
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