Bioactivity | Kv2.1-IN-1 (compound 80) is a potent inhibitor of Kv2.1, with the IC50 value of 0.07 μM, selectivity >130 fold over other K+, Na+, and Ca2+ ion channels[1]. |
Name | Kv2.1-IN-1 |
CAS | 2252448-93-2 |
Formula | C22H29N3O3 |
Molar Mass | 383.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jie Zhou, et al. Discovery of 2-Ethoxy-5-isobutyramido-N-1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects. J Med Chem. 2023 Dec 27. |