Bioactivity | VEGFR-2-IN-35 (compound 7) is a potent VEGFR-2 inhibitor with IC50=37 nM. VEGFR-2-IN-35 inhibits MCF-7 and HCT 116 cancer cells with IC50 values of 10.56 and 7.07 μM, respectively[1]. |
Target | IC50: 37 nM (VEGFR2) |
Name | VEGFR-2-IN-35 |
Formula | C25H19N3O3 |
Molar Mass | 409.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Elkaeed EB, et al. In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative. J Biomol Struct Dyn. 2023 Sep-Oct;41(16):7986-8001.. . |