| Bioactivity | BRL 52537 hydrochloride is a highly selective κ-Opioid receptor (KOR) agonist with Kis of 0.24 nM and 1560 nM for κ and μ subtypes, respectively. BRL 52537 hydrochloride decreases ischemia-evoked NO production as a potential mechanism of neuroprotection. BRL 52537 hydrochloride attenuates early stroke damage[1]. |
| Target | Ki: 0.24 nM (κ-Opioid receptor) and 1560 nM (μ-Opioid receptor) |
| Name | BRL 52537 hydrochloride |
| CAS | 112282-24-3 |
| Formula | C18H25Cl3N2O |
| Molar Mass | 391.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Toru Goyagi, et al. Neuroprotective kappa-opioid receptor agonist BRL 52537 attenuates ischemia-evoked nitric oxide production in vivo in rats. Stroke. 2003 Jun;34(6):1533-8. |
BRL 52537 hydrochloride
CAS: 112282-24-3 F: C18H25Cl3N2O W: 391.76
BRL 52537 hydrochloride is a highly selective κ-Opioid receptor (KOR) agonist with Kis of 0.24 nM and 1560 nM for κ an
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.