| Bioactivity | VEGFR-2-IN-15 (Compound 14b) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-15 arrests the HepG2 cell growth at the Pre-G1 phase and induces apoptosis[1]. |
| Invitro | VEGFR-2-IN-15 (Compound 14b) shows cytotoxic activities with IC50 values of 4.754 ± 0.21 µM and 4.61 ± 0.34 µM against MCF-7 and HepG2 cells, respectively[1].VEGFR-2-IN-15 shows the highest activities with VEGFR-2 protein concentrations of 705.7 pg/ml[1]. |
| Name | VEGFR-2-IN-15 |
| Formula | C23H18ClN3O4S |
| Molar Mass | 467.92 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |