Antagonist G TFA

CAS: F: C51H67F3N12O8S W: 1065.21

Antagonist G TFA is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antag

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Bioactivity	Antagonist G TFA is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy[1][2].
Invitro	Antagonist G (0-100 μM) induces apoptosis is redox-sensitive and caspase-dependently in SCLC cells[2].Antagonist G activates JNK1 in SCLC cells[2].Antagonist G is not intrinsically a free radical oxygen donor but stimulates free radical generation specifically within SCLC cells (6.2-fold) and increases the activity of the redox-sensitive transcription factor AP-1 by 61%[2]. Cell Viability Assay[2] Cell Line:
Name	Antagonist G TFA
Shortening	RW-{Me-Phe}-WLM-NH2
Formula	C51H67F3N12O8S
Molar Mass	1065.21
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Apoptosis inducer 6