| Bioactivity | VD5123 is a serine protease inhibitor. VD5123 inhibits TMPRS2, HGFA, matriptase, hepsin, factor Xa, and thrombin with IC50s of 11, 61, 90, 0.2, 955, and 13000 nM respectively. VD5123 can be used for anticancer research[1]. |
| In Vivo | VD5123 (13-20 mg/kg，腹腔注射) 的半衰期为 4.5 小时，在小鼠体内的化合物暴露时间超过 24 小时[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C39H46N8O6S |
| Molar Mass | 754.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Damalanka VC, et al. Mechanism-Based Macrocyclic Inhibitors of Serine Proteases. J Med Chem. 2024 Mar 13. |