Uridine 5'-monophosphate-13C9,15N2 (disodium)_product_DataBase

Bioactivity	Uridine 5'-monophosphate-13C9,15N2 (disodium) is the 13C and 15N labeled Uridine 5'-monophosphate disodium salt[1]. Uridine 5'-monophosphate disodium salt is component used for RNA synthesis[2].
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name	Uridine 5'-monophosphate-13C9,15N2 (disodium)
Formula	13C9H1115N2Na2O9P
Molar Mass	379.07
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Hozumi Y, et al. Orotate phosphoribosyltransferase localizes to the Golgi complex and its expression levels affect the sensitivity to anti-cancer drug 5-fluorouracil. Biomed Res. 2015;36(6):403-9.

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