| Bioactivity | UU-T01 is a selective inhibitor for β-Catenin/T-cell factor 4 protein-protein interaction (β-catenin/Tcf PPI) with an Ki value of 3.14 µM. UU-T01 is directly combined with β-catenin, and the KD value is 0.531 µM[1]. |
| Name | UU-T01 |
| CAS | 1417162-83-4 |
| Formula | C10H10N6O |
| Molar Mass | 230.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guo W, et al. Hot spot-based design of small-molecule inhibitors for protein-protein interactions. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2546-54. [2]. Cui C, et al. Is β-catenin a druggable target for cancer therapy?[J]. Trends in biochemical sciences, 2018, 43(8): 623-634. |