Bioactivity | USP30-I-1 is a selective inhibitor of USP30 with an IC50 value of 94 nM. USP30-I-1 can be used in the research of diseases with impaired mitophagy by targeting USP30[1]. |
Target | IC50: 94 nM (USP30). |
CAS | 2511541-78-7 |
Formula | C17H15N5O2 |
Molar Mass | 321.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. O'Brien D P, et al. Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor[J]. bioRxiv, 2024: 2024.07. 20.604388. |