PeptideDB

UP12

CAS: 443353-87-5 F: C23H16ClN3O3S W: 449.91

UP12 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 1.24 μM.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity UP12 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 1.24 μM[1].
CAS 443353-87-5
Formula C23H16ClN3O3S
Molar Mass 449.91
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Phan JM, et al., VCP activator reverses nuclear proteostasis defects and enhances TDP-43 aggregate clearance in multisystem proteinopathy models. J Clin Invest. 2024 May 23;134(14):e169039.