| Bioactivity | AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor[1]. | ||||||
| In Vivo | AV5124 在 20 mg/kg 的剂量下能保护 60% 的动物免于死亡，而在 50 mg/kg 的剂量下则能完全保护小鼠免受病毒引起的死亡。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||
| CAS | 2417851-93-3 | ||||||
| Formula | C25H21F2N3O7S2 | ||||||
| Molar Mass | 577.58 | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | RT, sealed storage, away from moisture and light
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| Reference | [1]. Andrei A Ivashchenko, et al. Synthesis, inhibitory activity and oral dosing formulation of AV5124, the structural analogue of influenza virus endonuclease inhibitor baloxavir. J Antimicrob Chemother. 2021 Mar 12;76(4):1010-1018. |
AV5124
CAS: 2417851-93-3 F: C25H21F2N3O7S2 W: 577.58
AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor
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