| Bioactivity | UNC8899 is a VHL-recruiting STING PROTAC degrader (DC50: 0.0.924 μM). UNC8899 can be used for viral or bacterial infection research (Blue: VHL ligand, Black: linker; Pink: STING inhibitor)[1]. |
| Invitro | UNC8899 (3 μM，8-24 小时) 在 Caki-1 细胞中诱导 STING 降解[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> UNC8899 相关抗体: |
| Formula | C71H91N17O13S |
| Molar Mass | 1422.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhu Z, et al. Development of VHL-recruiting STING PROTACs that suppress innate immunity. Cell Mol Life Sci. 2023 May 14;80(6):149. |