| Bioactivity | UMK57 is a small molecule compound that specifically promotes k-MT attachment error correction to inhibit chromosome missegregation, which can improve chromosome segregation fidelity by destabilizing kinetochore microtubule (k-MT) attachment during mitosis[1]. |
| Name | UMK57 |
| CAS | 342595-74-8 |
| Formula | C17H17N3S |
| Molar Mass | 295.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bernardo Orr, et al. Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells. Cell Rep. 2016 Nov 8;17(7):1755-1763. |