Bioactivity | NVOC cage-TMP-Halo is a cell-permeable and photoactivatable protein dimerization inducer. NVOC cage-TMP-Halo can rapidly and reversibly control protein localization in living cells. NVOC cage-TMP-Halo can be used for dynamic cellular processes research[1]. | ||||||||||||
Invitro | NVOC cage-TMP-Halo (20μM, 15, 30, and 60分钟) 在 HeLa 细胞中空间上精确操纵蛋白质定位的能力[1]。NVOC cage-TMP-Halo (20μM, 60 min) 在表达 CENPB-GFP-Haloenzyme 和mCherry-eDHFR 的 HeLa细胞中以t1/2 约为 15 s 的速率向着丝粒显著募集 mCherry-eDHFR[1]。 0 --> NVOC cage-TMP-Halo 相关抗体: | ||||||||||||
Name | NVOC cage-TMP-Halo | ||||||||||||
CAS | 2137894-98-3 | ||||||||||||
Formula | C40H56ClN7O13 | ||||||||||||
Molar Mass | 878.36 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
|
||||||||||||
Reference | [1]. Ballister ER, et al. Localized light-induced protein dimerization in living cells using a photocaged dimerizer. Nat Commun. 2014 Nov 17;5:5475. |