| Bioactivity | UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM[1]. |
| Target | IC50: 3.5 µM (DNA gyrase catalytic). |
| Name | UIAA-II-232 |
| CAS | 2428407-03-6 |
| Formula | C20H24FN5O3 |
| Molar Mass | 401.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Aguirre AL, et al. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28(10):115439. |