| Bioactivity | UBX-382 is an orally available proteolysis-targeting chimeras (PROTACs) that target BTK to inactivate B-cell receptor signaling. UBX-382 shows superior degradation activity for wild-type and mutant BTK proteins and shows anti-cancer activity in murine xenograft models of TMD-8 cells[1]. |
| Name | UBX-382 |
| CAS | 2884554-45-2 |
| Formula | C42H44N10O4 |
| Molar Mass | 752.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lim YS, et al. Orally bioavailable BTK PROTAC active against wild-type and C481 mutant BTKs in human lymphoma CDX mouse models. Blood Adv. 2023;7(1):92-105. |
UBX-382
CAS: 2884554-45-2 F: C42H44N10O4 W: 752.86
UBX-382 is an orally available proteolysis-targeting chimeras (PROTACs) that target BTK to inactivate B-cell receptor si
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This product is for research use only, not for human use. We do not sell to patients.