| Bioactivity | Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinase activity from human melanoma cell lysates[1]. |
| Target | IC50: 1.6 μM (human tyrosinase) |
| Invitro | Tyrosinase-IN-10 (Compound 23) (0-100 μM; 96 h) 抑制 MNT-1 全细胞黑素生成，IC50 为 29 μM, 对 MNT-1 的细胞毒性 CC50 为 91 μM[1]。 Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Tyrosinase-IN-10 |
| CAS | 2873418-48-3 |
| Formula | C16H12O4 |
| Molar Mass | 268.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Roulier B, et al. Resorcinol-based hemiindigoid derivatives as human tyrosinase inhibitors and melanogenesis suppressors in human melanoma cells. Eur J Med Chem. 2023 Jan 15;246:114972. |
Tyrosinase-IN-10
CAS: 2873418-48-3 F: C16H12O4 W: 268.26
Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinas
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