| Bioactivity | BChE-IN-15 (Compound 6) is a pseudo-irreversible and covalent BChE inhibitor with an IC50 of 1.76 nM against hBChE [1]. |
| Invitro | BChE-IN-15 (Compound 6) (0.5-50 μM; 48 h) 显示对 SH-SY5Y 和 HepG2 细胞的细胞毒性[1]。 Cell Cytotoxicity Assay[1] Cell Line: |
| Name | BChE-IN-15 |
| Formula | C22H33N3O2 |
| Molar Mass | 371.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Meden A, et al. Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead. Eur J Med Chem. 2022 Dec 24;247:115048. |