Tylvalosin_product_DataBase

Bioactivity	Tylvalosin (Acetylisovaleryltylo?sin) is a broad-spectrum macrolide antibiotic that has antibacterial activity. Tylvalosin is an antiviral agent and can be used for PRRSV infection. . Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, relieves oxidative stress, and relieves acute lung injury by suppression of NF-κB activation[1][2].
Name	Tylvalosin
CAS	63409-12-1
Formula	C53H87NO19
Molar Mass	1042.25
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Albert Philip Adrian Mockett, et al. Use of tylvalosin as antiviral agent. Patent. WO2008007104. [2]. Zhao Z, et al. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. Biochem Pharmacol. 2014 Jul 1;90(1):73-87. [3]. Moges R, et al. Anti-Inflammatory Benefits of Antibiotics: Tylvalosin Induces Apoptosis of Porcine Neutrophils and Macrophages, Promotes Efferocytosis, and Inhibits Pro-Inflammatory CXCL-8, IL1α, and LTB4 Production, While Inducing the Release of Pro-Resolving Lipoxin A4 and Resolvin D1. Front Vet Sci. 2018 Apr 11;5:57.

PeptideDB