| Bioactivity | Tyk2-IN-8 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease[1]. |
| Name | Tyk2-IN-8 |
| CAS | 2704587-24-4 |
| Formula | C20H19D3N8O3 |
| Molar Mass | 425.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xiangyang Chen, et al. Heterocyclic compounds for inhibiting tyk2 activities. WO2021180072A1. |
Tyk2-IN-8
CAS: 2704587-24-4 F: C20H19D3N8O3 W: 425.46
Tyk2-IN-8 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3
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