| Bioactivity | Tubulin polymerization-IN-57 (compound 5a) is a tubulin inhibitor and is an α-naphthoxy-substituted carbendazim (HY-13582) derivative. Tubulin polymerization-IN-57 induces mitotic arrest and inhibits cancer cell proliferation[1]. |
| Name | Tubulin polymerization-IN-57 |
| CAS | 95385-38-9 |
| Formula | C19H15N3O3 |
| Molar Mass | 333.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cano-González L et al. Structure-Based Optimization of Carbendazim-Derived Tubulin Polymerization Inhibitors through Alchemical Free Energy Calculations. J Chem Inf Model. 2023 Nov 27;63(22):7228-7238. |
Tubulin polymerization-IN-57
CAS: 95385-38-9 F: C19H15N3O3 W: 333.34
Tubulin polymerization-IN-57 (compound 5a) is a tubulin inhibitor and is an α-naphthoxy-substituted carbendazim (HY-135
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