| Bioactivity | COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC50 of 0.4 μM[1][2]. |
| Target | IC50: 0.4 μM (COX-2). |
| Name | COX-2-IN-36 |
| CAS | 189954-93-6 |
| Formula | C17H22O5S |
| Molar Mass | 338.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lushi Tan, et al. Practical enantioselective synthesis of a COX-2 specific inhibitor. TetrahedronVolume 58, Issue 37, 9 September 2002, Pages 7403-7410. [2]. Yves Leblanc, et al. Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3317-20. |