| Bioactivity | Tubulin inhibitor 17 (Compound 3b) is a tubulin polymerization inhibitor with an IC50 of 12.38 µM. Tubulin inhibitor 17 has anticancer activities and induces cell apoptosis[1]. |
| Invitro | Tubulin inhibitor 17 (Compound 3b) (0-10 µM, 0-72 h) displays antiproliferative activities against cancer cells and inhibits colony formation of HepG-2 cells[1].Tubulin inhibitor 17 (0-2.5 µM) inhibits tubulin polymerization in a concentration-dependent manner[1].Tubulin inhibitor 17 (0-1 µM, 12 h) induces the collapse of the microtubule networks in a dose-dependent manner[1].Tubulin inhibitor 17 (0-5 μM, 24 h) induces cell cycle arrest at G2/M phase and inhibits cell migration in HepG-2 cells[1].Tubulin inhibitor 17 (0-5 μM, 48 h) induces HepG-2 cell apoptosis[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | Tubulin inhibitor 17 |
| Formula | C17H16N2O |
| Molar Mass | 264.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |