Bioactivity | Trimethyllysine-d9is the deuterium labeledTrimethyllysine(HY-143711)[1]. Trimethyllysine is an important post-translationally modified amino acid, involving in carnitine biosynthesis and epigenetic processes[2]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 |
Name | Trimethyllysine-d9 |
CAS | 1182037-78-0 |
Formula | C9H11D9N2O2 |
Molar Mass | 197.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Maas MN, et al. Trimethyllysine: From Carnitine Biosynthesis to Epigenetics. Int J Mol Sci. 2020 Dec 11;21(24):9451. |