| Bioactivity | Topoisomerase II inhibitor 17 (compound 4c) is an inhibitor of thiazolopyrimidine topoisomerase (Topoisomerase) Top II (IC50: 0.23 μM). Topoisomerase II inhibitor 17 can significantly cause cell cycle disruption and apoptosis[1]. |
| Target | IC50: 0.23 μM (Top II) |
| Name | Topoisomerase II inhibitor 17 |
| Formula | C25H22Cl3N3O5S |
| Molar Mass | 582.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. El-Zoghbi MS, et al. Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2175209. |
Topoisomerase II inhibitor 17
CAS: F: C25H22Cl3N3O5S W: 582.88
Topoisomerase II inhibitor 17 (compound 4c) is an inhibitor of thiazolopyrimidine topoisomerase (Topoisomerase) Top II (
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