PeptideDB

Tivumecirnon

CAS: 2174938-78-2 F: C24H27Cl2F3N6O W: 543.41

Tivumecirnon (FLX475) is a potent CCR4 antagonist that blocks regulatory T cells that interfere with effective antitumor
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Tivumecirnon (FLX475) is a potent CCR4 antagonist that blocks regulatory T cells that interfere with effective antitumor immune responses and has antitumor activity[1].
Name Tivumecirnon
CAS 2174938-78-2
Formula C24H27Cl2F3N6O
Molar Mass 543.41
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Hilary Plake BECK, et al. Chemokine receptor modulators and uses thereof. WO2018022992.