| Bioactivity | Tirotundin (Tagitinin D) is a potent anti-inflammatory agent. Tirotundin inhibits the activation of NF-Kβ[1]. |
| Invitro | Tirotundin (compound 3) (5, 10, 20, 50 µM; 1 h；随后用 TNF-α 刺激一小时) 在浓度为 50 µM 时完全抑制 NF-Kβ 的激活[1]。 |
| Name | Tirotundin |
| CAS | 56377-67-4 |
| Formula | C19H28O6 |
| Molar Mass | 352.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rüngeler P, et al. Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kappa B and enzymes of the arachidonic acid pathway as targets. Planta Med. 1998 Oct;64(7):588-93. |