| Bioactivity | Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1]. |
| Name | Tiagabine hydrochloride hydrate |
| CAS | 145821-57-4 |
| Formula | C20H28ClNO3S2 |
| Molar Mass | 430.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Braestrup C, et al. (R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier. J Neurochem. 1990 Feb;54(2):639-47. |
Tiagabine hydrochloride hydrate
CAS: 145821-57-4 F: C20H28ClNO3S2 W: 430.02
Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with I
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This product is for research use only, not for human use. We do not sell to patients.