| Bioactivity | Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36[1]. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation[2]. | ||||||||||||
| Name | Thiolutin | ||||||||||||
| CAS | 87-11-6 | ||||||||||||
| Formula | C8H8N2O2S2 | ||||||||||||
| Molar Mass | 228.29 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Thiolutin
CAS: 87-11-6 F: C8H8N2O2S2 W: 228.29
Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. T
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