| Bioactivity | Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc is a conjugate of E3 ligase ligand and linker, which contains Thalidomide-based CEREBLON ligand and PEG inker. Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc can be used to synthesize PROTAC degrader JB300 (HY-137341)[1]. |
| CAS | 1957235-73-2 |
| Formula | C26H34N4O10 |
| Molar Mass | 562.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bozilovic, et al. "Novel, highly potent PROTACs targeting AURORA-A kinase." Current Research in Chemical Biology 2 (2022): 100032. |
Thalidomide-O-CH2-CO-NH-C2-PEG2-NH-Boc
CAS: 1957235-73-2 F: C26H34N4O10 W: 562.57
Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc is a conjugate of E3 ligase ligand and linker, which contains Thalidomide-based CE
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