| Bioactivity | Itaconic acid prodrug-1 (Compound P2) is an orally active prodrug of Itaconic acid (HY-Y0520) that efficiently delivers the active ingredient Itaconic acid to skin tissue following oral administration. Itaconic acid prodrug-1 possesses immunomodulatory properties, significantly inhibiting Poly(I:C)/IFNγ-induced inflammatory cytokines in human epidermal keratinocytes. Itaconic acid prodrug-1 can be utilized for the research of alopecia areata and other inflammatory skin diseases[1]. |
| CAS | 2641132-66-1 |
| Formula | C15H22O10 |
| Molar Mass | 362.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lee C B, et al. Discovery of Orally Available Prodrugs of Itaconate and Derivatives[J]. Journal of Medicinal Chemistry, 2025. |
Itaconic acid prodrug-1
CAS: 2641132-66-1 F: C15H22O10 W: 362.33
Itaconic acid prodrug-1 (Compound P2) is an orally active prodrug of Itaconic acid (HY-Y0520) that efficiently delivers
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