| Bioactivity | Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo. |
| Name | Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium |
| CAS | 2611373-74-9 |
| Formula | C29H55N6O5PSi |
| Molar Mass | 626.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937. |
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
CAS: 2611373-74-9 F: C29H55N6O5PSi W: 626.84
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human
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