| Bioactivity | PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1]. |
| Target | IC50: 12.1 μM (PknB) |
| Invitro | PknB-IN-2 (Compound 10) shows encouraging growth inhibition activity toward the M. tuberculosis H37Rv strain, with a MIC value of 6.2 μg/mL[1]. |
| Name | PknB-IN-2 |
| CAS | 500015-22-5 |
| Formula | C28H32N2O4 |
| Molar Mass | 460.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Thongdee P, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22. |