| Bioactivity | Tauro-Obeticholic acid-d5 (sodium) is deuterium labeled Tauro-Obeticholic acid. Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1]. |
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| Name | Tauro-Obeticholic acid-d5 (sodium) |
| Formula | C28H44D5NO6S |
| Molar Mass | 532.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6. |
Tauro-Obeticholic acid-d5 (sodium)
CAS: F: C28H44D5NO6S W: 532.79
Tauro-Obeticholic acid-d5 (sodium) is deuterium labeled Tauro-Obeticholic acid. Tauro-Obeticholic acid is an active meta
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