PeptideDB

Taltobulin intermediate-10

CAS: 1822592-72-2 F: C18H27NO4 W: 321.41

Taltobulin intermediate-10 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin co
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Bioactivity Taltobulin intermediate-10 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Name Taltobulin intermediate-10
CAS 1822592-72-2
Formula C18H27NO4
Molar Mass 321.41
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.