| Bioactivity | Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis. |
| Invitro | Taccalonolide E (5 or 10 μM; 18 h) 在 A-10 细胞中导致间期细胞中细胞微管密度增加，形成厚束微管[1]。Taccalonolide E (1 or 5 μM; 18 h) 导致 A-10 和 HeLa 细胞出现异常多极有丝分裂纺锤体[1]。Taccalonolide E (5 μM; 6-24 h) 在 G2-M 期阻滞细胞周期[1]。Taccalonolide E (0.5-5 μM; 18 h) 在间期细胞中启动微核化[1]。Taccalonolide E (48 h) 抑制癌细胞增殖[1]。Taccalonolide E (10 μM; 1 h) 导致 MDA-MB-435 细胞微管蛋白聚合[1]。Taccalonolide E (5 μM; 4-30 h) 启动 Bcl-2 磷酸化，MAPK 激活和凋亡[1]。 Cell Cycle Analysis[1] Cell Line: |
| Name | Taccalonolide E |
| CAS | 134954-57-7 |
| Formula | C34H44O12 |
| Molar Mass | 644.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |