Bioactivity | TRPA1-IN-2 (compound 1) is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM. TRPA1-IN-2 shows anti-inflammation activity[1]. | ||||||||||||
In Vivo | TRPA1-IN-2 (90 mg/kg;小鼠腹腔注射;大鼠腹腔注射 30 mg/kg;100 mg/kg;口服) 显示出抗炎活性[1]。 Animal Model: | ||||||||||||
Name | TRPA1-IN-2 | ||||||||||||
CAS | 2415206-22-1 | ||||||||||||
Formula | C24H25F3N4O | ||||||||||||
Molar Mass | 442.48 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. YunFeng Cheng, et al. Heteroaromatic acetamide derivative, and preparation and use thereof. WO2020244460A1. |