PeptideDB

TRPA1-IN-2

CAS: 2415206-22-1 F: C24H25F3N4O W: 442.48

TRPA1-IN-2 (compound 1) is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM. TRPA1-IN-2 shows a
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Bioactivity TRPA1-IN-2 (compound 1) is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM. TRPA1-IN-2 shows anti-inflammation activity[1].
In Vivo TRPA1-IN-2 (90 mg/kg;小鼠腹腔注射;大鼠腹腔注射 30 mg/kg;100 mg/kg;口服) 显示出抗炎活性[1]。 Animal Model:
Name TRPA1-IN-2
CAS 2415206-22-1
Formula C24H25F3N4O
Molar Mass 442.48
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. YunFeng Cheng, et al. Heteroaromatic acetamide derivative, and preparation and use thereof. WO2020244460A1.